M. V. Ivanochko¹, M. M. Bayliak¹, V. I. Lushchak^1,2*

¹Department of Biochemistry and Biotechnology,
Vasyl Stefanyk Precarpathian National University, Ivano-Frankivsk, Ukraine;
²Research and Development University, Ivano-Frankivsk, Ukraine;
*e-mail: volodymyr.lushchak@pnu.edu.ua

Received: 03 September 2024; Revised: 11 November 2024;
Accepted: 21 November 2024; Available on-line: 17 December 2024

Biologically active food components are now considered to be remedies for the prevention and treatment of metabolic disorders of different etiology. The aim of this review was to analyze the current data on the application of isothiocyanate sulforaphane, found in broccoli and other cruciferous plants, for the treatment of T2DM, obesity, and their comorbidities with the presentation of established molecular, particularly dependent on NF-E2-related factor-2 (Nrf2), and signaling mechanisms of therapeutic effects.