Tag Archives: atomic-force microscopy

Effect of fullerene C(60) on ATPase activity and superprecipitation of skeletal muscle actomyosin

06.10.2015   Uncategorized   No comments

K. S. Andreichenko1, S. V. Prylutska1, K. O. Medynska1, K. I. Bogutska1,
N. E. Nurishchenko1, Yu. I. Prylutskyy1, U. Ritter2, P. Scharff2

Joint Ukrainian-German Center on Nanobiotechnology
1Taras Shevchenko National University of Kyiv, Ukraine;
e-mail: prylut@ukr.net;
2Technical University of Ilmenau, Institute of Chemistry
and Biotechnology, Germany

Creation of new biocompatible nanomaterials, which can exhibit the specific biological effects, is an important complex problem that requires the use of last accomplishments of biotechnology. The effect of pristine water-soluble fullerene C60 on ATPase activity and superprecipitation reaction of rabbit skeletal muscle natural actomyosin has been revealed, namely an increase of actomyosin superprecipitation and Мg2+, Са2+– and K+-ATPase activity by fullerene was investigated. We conclude that this finding offers a real possibility for the regulation of contraction-relaxation of skeletal muscle with fullerene C60.

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Effect of С(60) fullerene on metabolic and proliferative activity of PKE cell line

11.06.2015   Uncategorized   No comments

I. V. Belochkina1, I. О. Ishchenko1, S. V. Prylutska2, K. I. Bogutska2,
V. V. Cherepanov3, B. P. Sandomirskiy1, Yu. I. Prylutskyy2

1Institute for Problems of Cryobiology and Cryomedicine,
National Academy of Sciences of Ukraine, Kharkiv;
e-mail: bsan38@yahoo.com;
2Taras Shevchenko National University of Kyiv;
e-mail: prylut@ukr.net;
3Institute of Physics, National Academy of Sciences of Ukraine, Kyiv

The effect of С60 fullerene aqueous colloid solution (C60FAS) on activity of redox and proliferative processes in PKE (transplantable cell line of pig kidney embryo) cells has been studied. In particular, it was established that the presence of С60 fullerene (127 μМ) in culturing medium of PKE cells during 48 h did not change their ability to reduce non-toxic АlamarBlue redox indicator and proliferative acti­vity.

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