R. Yu. Marunych*, O. O. Hrabovskyi, G. K. Bereznytskyj,
L. V. Pyrogova, G. K. Gogolinskaya, Ye. M. Makogonenko

Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv;
*e-mail: rostmarbiotech@gmail.com

Received: 29 September 2020; Accepted: 07 July 2021

The review focuses on chloride-binding structures in the proteins of bacteria, plants, viruses and animals. The structure and amino acid composition of the chloride-binding site and its role in the functioning of structural, regulatory, transport, receptor, channel proteins, transcription factors and enzymes are considered. Data on the important role of chloride-binding structures and chloride anions in the polymerization of fibrin are presented.