Yu. E. Kolupaev^1,2*, L. I. Relina¹, A. I. Oboznyi¹, N. I. Ryabchun¹,
N. I. Vasko¹, V. P. Kolomatska¹, O. Yu. Leonov¹

¹Yuriev Plant Production Institute, National Academy
of Agrarian Sciences of Ukraine, Kharkiv;
²Poltava State Agrarian University, Poltava, Ukraine;
*e-mail: plant_biology@ukr.net

Received: 25 April 2025; Revised: 21 May 2025;
Accepted: 11 June 2025; Available on-line: 07 July 2025

Drought is one of the main factors limiting agricultural production and leading to crop losses. Wheat, being a source of food for over half of the world’s population, is a plant species that is very susceptible to drought. In this regard, research into the species-specific stress metabolites and physiological and biochemical mechanisms of drought tolerance is of particular practical interest. This review comprehensively examines the roles of soluble carbohydrates, proline, polyamines, and GABA, as well as their functional interplay, in adaptation of wheat and other plant species to drought.