Ukr.Biochem.J. 2013; Volume 85, Issue 1, Jan-Feb, pp. 96-106
doi: http://dx.doi.org/10.15407/ubj85.01.096
Stem cells and receptors connected with G-proteins – in the vanguard of science again
S. I. Romanyuk, S. V. Komisarenko
Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv;
e-mail: sir@biochem.kiev.ua; svk@biochem.kiev.ua
The article presents the information about scientific activity of John B. Gurdon and Shinya Yamanaka, the Nobel Prize laureats for Physiology or Medicine in 2012 for the discovery that fully differentiated cells can be reprogrammed into pluripotent cells; and also Robert J. Lefkowitz and Brian K. Kobilka, the Nobel Prize laureats for Chemistry in 2012 for studies of G-protein-coupled receptors.
Keywords: "theory of the ternary complex", cell differetiation, G-protein-coupled receptors (GPCRs), G-proteins, reprogramming of differentiated cells into pluripotent cells, stem cells
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