Tag Archives: A. Szent-Györgyi

The contribution of the Nobel prize laureates to the development of knowledge of vitamin biochemistry: Ch. Eijkman, F. G. Hopkins, A. Szent-Györgyi, W. Haworth, P. Karrer, R. Kuhn, H. Dam, E. A. Doisy, G. Minot, W. Murphy, G. Whipple, D. Hodgkin, R. Woodward

V. M. Danilova, R. P. Vynogradova, S. V. Komisarenko

Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv;
e-mail: valdan@biochem.kiev.ua

In the first half of the 20th century, the experimental research of chemists, biochemists and physiologists in collaboration with doctors led to the discovery of a new class of biologically active compounds – vitamins. Many of these scientists were awarded the Nobel Prizes. Thanks to their efforts, almost all currently known vitamins (B1, B2, B6, B9, B12, C, A, E, K) were identified, their structure and the mechanism of biological action were characteri­zed. Many vitamins were found to serve as coenzymes in important biochemical conversions. This article talks about the history of the discovery of the most familiar vitamins and scientists involved in their research. The contribution made by these distinguished scientists to the development of modern­ biochemical science, in particular, vitaminology, cannot be overestimated.

The contribution of the Nobel Prize laureates to the development of dynamic biochemistry and bioenergetics. E. Buchner, A. Kossel, R. Willstätter, O. Meyerhof, A. Hill, O. Warburg, A. Szent-Györgyi

V. M. Danilova, R. P. Vynogradova, S. V. Komisarenko

Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiyv;
e-mail: valdan@biochem.kiev.ua

Received: 29 November 2018; Accepted: 13 December 2018

Thanks to the great discoveries of the Nobel laureates of the first half of the 20th century – E. Buchner, A. Kossel, R. Willstätter, O. Meyerhof, A. Hill, O. Warburg, A. Szent-Györgyi, we have gained a deep understanding of the mechanisms of organic­ substances conversion and oxidation in living­ organisms­. This article gives an analysis of the research activity of these distinguished scientists, who, through decoding the main ways of conver­ting carbohydrates and energy in living organisms, laid the foundations of dynamic biochemistry and bioener­getics (one of the branches of biochemical science).