Ukr.Biochem.J. 2013; Volume 85, Issue 1, Jan-Feb, pp. 71-78


The glutathione system in the blood of rats and morphological changes of the pancreas under experimental acute and chronic pancreatitis

V. A. Makarchuk1, G. O. Ushakova2, O. O. Krylova1

1SI Institute of Gastroenterology, National Academy of Medical Sciences of Ukraine, Dnipropetrovsk;
2Oles’ Gonchar Dnipropetrovsk National University, Ukraine;

In experiment on laboratory rats the models of acute and chronic pancreatitis were developed to study the changes of lipoperoxidation-antioxidant protection system depending on morphological changes of the pancreas. The acute and chronic pancreatitis is accompanied with intensification of lipoperoxidation and gradual inhibition of antioxidant system due to development of subsequent chronization of the pathological process.

Keywords: , , ,


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