Ukr.Biochem.J. 2025; Volume 97, Issue 4, Jul-Aug, pp. 22-33

doi: https://doi.org/10.15407/ubj97.04.022

Chemerin-adiponectin axis in hypothyroidism

10.09.2025   Uncategorized   No comments

M. K. Najim1*, A. F. Al-Shukri2

1Department of Medical Laboratory Technology, College of Health and Medical Technology,
Al-Furat Al-Awsat Technical University, Kufa, Iraq;
Thi-Qar Health Directorate, Al-Rifae Teaching Hospital;
*e-mail: murtadha.najeem.chm@student.atu.edu.iq;
2Department of Medical Laboratory Technology, College of Health and Medical Technology,
Al-Furat Al-Awsat Technical University, Kufa, Iraq;
e-mail: kin.ebt@atu.edu.iq

Received: 09 April 2025; Revised: 30 June 2025;
Accepted: 12 September 2025; Available on-line: 17 September 2025

Hypothyroidism disrupts energy and metabolism due to insufficient thyroid hormones production, leading to metabolic disorders such as insulin resistance and dyslipidemia. Recent studies have demonstrated the impact of adipokines, chemerin and adiponectin on thyroid function. This review analyzes the involvement of these hormones in the metabolic and inflammatory complications of hypothyroidism, their effects and interactions through complex signaling pathways, as well as their possible contribution to the etiology and treatment of hypothyroidism, considering the importance of integrating biomarker data.

Keywords: , , , ,

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