V. O. Chernyshenko*, V. I. Gryshchuk

Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine,
Department of Protein Structure and Function, Kyiv;
*e-mail: bio.cherv@gmail.com

Received: 02 July 2025; Revised: 30 July 2025;
Accepted: 30 October 2025; Available on-line: 2025

This overview is dedicated to the history of the Department of Protein Structure and Function at the Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. It outlines the department’s main scientific objectives and highlights its key achievements. In particular, it describes research related to patient blood management, fundamental studies of fibrinogen structure and function, the development of next-generation antithrombotic prototypes, as well as the creation and clinical testing of diagnostic assays. Special attention is given to inventions and studies aimed at addressing pressing social issues, including post-traumatic stress disorder and the consequences of COVID-19. The importance of maintaining continuity in hemostasis research is emphasized, as it enables the generation of unique scientific results and their implementation in medical practice.

Keywords: anti-bleeding agents, blood coagulation, enzyme, fibrin polymerization, fibrinogen, patient blood management, protein