N. V. Khimich, A. I. Gоrdienko

State Institution S. I. Georgievsky Crimea State Medical University, Simferopol, Ukraine;
e-mail: uu4jey@csmu.strace.net

It is established, that native and chaotropically modified immunoglobulins essentially differ by avidity and character of competitive inhibition of binding with protein (оvalbumin), glycolipid (lipopolysaccharides) antigens and native double-string DNA. Apparently, it is connected with structural and functional distinctions of their antigen-binding centres.