Ukr.Biochem.J. 2022; Volume 94, Issue 1, Jan-Feb, pp. 5-13

doi: https://doi.org/10.15407/ubj94.01.005

Pyridoxine, folate, and cobalamin and the condition of the innate and acquired immunity

28.04.2022   Uncategorized   No comments

M. I. Kinash, O. R. Boyarchuk

Ivan Horbachevsky Ternopil National Medical University, Ukraine;
e-mail: kinash@tdmu.edu.ua, boyarchuk@tdmu.edu.ua

Received: 23 September 2021; Accepted: 21 January 2022

The immune response to the pathogen depends on the state and coordinated activity of innate and acquired immunity. To date, the positive role of many micronutrients (vitamins and minerals) in maintaining homeostasis of the human immune system has been proven. The aim of the review was to analyze the main manifestations of vitamins B6, B9, B12 influence on the state of innate and adaptive immunity. These vitamins play an important role in the synthesis of DNA and RNA, cytokines and immunoglobulins, thus maintaining the proper state of the immune system. The functioning of the main links of specific and nonspecific immunity at the normal vitamin status and at pyridoxine, folate and cobalamin deficiency is compared.

Keywords: , , ,

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