Tag Archives: adaptation

Carbohydrate and nitrogenous metabolism condition in the rat tissue under experimental rhabdomyolysis

P. A. Kaliman, S. M. Okhrimenko

Karazin Kharkiv National University, Ukraine;
e-mail: s.okhrimenko@mail.ru

Some effects of glycerol injection on indices of the condition of the thiol-disulfide system as well as carbohydrate and nitrogen metabolism in rats in vivo were studied. A decrease was revealed in levels of non-protein SH-groups in the liver, kidney and heart, as well as of protein SH-groups in the kidney and heart of rats following glycerol injection. That might be connected with SH-group oxidation under the excessive arrival of free haem into tissues under rhabdomyolysis. A decrease in glycogen and  increase in tyrosine aminotransferase activity in the liver were observed. Activation of nitrogenous metabolism following glycerol injection is indicated by the increase of aminotransferase activity in organs, and concentration of blood urea. High concentration of creatinine in the rat serum can reflect malfiltration in kidneys.

Lipoxygenases and plant cell metabolism regulation

I. V. Pokotylo, Y. S. Kolesnikov, M. V. Derevyanchuk, A. I. Kharitonenko, V. S. Kravets

Institute of Bioorganic Chemistry and Petrochemistry,
National Academy of Sciences of Ukraine, Kyiv;
e-mail: kravets@bpci.kiev.ua

Lipoxygenases are widespread plant enzymes that catalyze the peroxidation of polyunsaturated fatty acids. This reaction is pivotal in the enzymatic cascade that leads to production of numerous metabolism regulators named oxylipins. The activity of these biologically active substances is directly associated with defence reactions in conditions of biotic and abiotic stresses as well as with the regulation of plant growth, propagation and senescence. In this review the contemporary notions about lipoxygenases­ classification, structure and catalytic properties are summarized. The features of enzyme activity regulation by transcriptional and posttranslational mechanisms in addition to the role of lipoxygenase catalysis in plant cell signalling are discussed.