Ukr.Biochem.J. 2013; Volume 85, Issue 2, Mar-Apr, pp. 105-109


Biochemical changes in rats under the influence of cesium chloride

N. M. Melnikova, O. V. Yermishev

National University of Life and Environmental Sciences of Ukraine, Kyiv;

Cesium is lately accumulated actively in the environment, but its influence on human and ani­mal organism is the least studied among heavy metals. It is shown that the action of cesium chloride in rats caused significant changes in blood chemistry, which are characterized by a decrease of total protein content, pH, an increase in the level of urea, creatinine, glucose and total hemoglobin. The results showed that potassium content in all the studied organs and tissues of poisoned rats decreases under the action of cesium chloride. Histological examination of the heart tissue in rats poisoned with cesium chloride indicates the onset of pathology of cardiovascular system. It was found out that use of the drug “Asparkam” reduces the negative effect of cesium chloride on the body of rats.

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