Ukr.Biochem.J. 2022; Volume 94, Issue 4, Jul-Aug, pp. 54-60

doi: https://doi.org/10.15407/ubj94.04.054

Lipid parameters in the blood of coronary artery diseases patients depending on age and dietary components: a case study

03.11.2022   Uncategorized   No comments

S. Prasad1, M. K. Mishra2*, A. K. Yadav2

1Department of Biochemistry, K. J. Somaiya Medical College and Research Mumbai, India;
2Department of Biochemistry, Shri Ramakrishna Institute of Medical Science
and Sanaka Hospitals, Durgapur, West Bengal, India;
*e-mail: mritunjaymishra007@gmail.com

Received: 19 March 2022; Revised: 13 September 2022;
Accepted: 04 November 2022; Available on-line: 14 November 2022

Coronary artery disease (CAD) is the major cause of mortality worldwide and is defined as an elevated level of atherogenic cholesterol and low levels of HDL cholesterol. However, very few studies have been conducted in India on the association of blood lipid profile with age and diet. The study aims to estimate lipid parameters in the blood of CAD patients aged 40-70 years on different diets. Lipid parameters were analyzed by enzymatic method on EM-200 fully automated Biochemistry analyzer. The data obtained showed that the majority of patients who suffered from CAD were between the age group of 51-60 years. Patients with CAD had altered lipid profiles, with higher levels of serum TGs, total cholesterol and low levels of HDL. Vegetarians have been found to have reduced lipid risk factors for coronary heart disease compared to patients on a mixed diet.

Keywords: , , , , ,

References:

  1. Fredrickson DS. An international classification of hyperlipidemias and hyperlipoproteinemias. Ann Intern Med. 1971;75(3):471-472. PubMed, CrossRef
  2. Kulkarni P (2015) Family History of Coronary Artery Disease as an Additional Risk Factor Associated with Coronary Artery Disease: A Descriptive Observational Study. J Clin Trial Cardiol. 2015; 2(1): 1-2. CrossRef
  3. World Health Organization (2009) Global health risks: Mortality and burden of disease attributable to selected major risks. WHO, Geneva (5).
  4. Saha MS, Sana NK, Shaha RK. Serum Lipid Profile of Hypertensive Patients in the Northern Region of Bangladesh. J Bio-Sci. 2006;14:93-98.
    CrossRef
  5. Amani R, Noorizadeh M, Rahmanian S, Afzal N, Haghighizadeh MH. Nutritional related cardiovascular risk factors in patients with coronary artery disease in Iran: a case-control study. Nutr J. 2010;9:70. PubMed, PubMedCentral, CrossRef
  6. Vinay BC, Shastrya CS, Kodangala S, Mateti UV, Bhat K. Association of diet and lipid profile among coronary heart disease patients. Clin Epidemiol Global Health. 2020;8(4):1321-1324. CrossRef
  7. World Health Organization. Diet, nutrition and the prevention of chronic diseases. Report of a joint WHO/FAO expert consultation. WHO technical report series, vol 916. Geneva: World Health Organization, 2003;916. 149 p.
  8. Barr AJ. The biochemical basis of disease. Essays Biochem. 2018;62(5):619-642. PubMed, PubMedCentral, CrossRef
  9. Dobson A, Filipiak B, Kuulasmaa K, Beaglehole R, Stewart A, Hobbs M, Parsons R, Keil U, Greiser E, Korhonen H, Tuomilehto J. Relations of changes in coronary disease rates and changes in risk factor levels: methodological issues and a practical example. Am J Epidemiol. 1996;143(10):1025-1034. PubMed, PubMedCentral, CrossRef
  10. WHO, Diabetes; www.who.int/mediacentre/factsheets/fs236/en/, 9/29/2014.
  11. Wake R, Takeuchi M, Yoshikawa J, Yoshiyama M. Effects of gender on prognosis of patients with known or suspected coronary artery disease undergoing contrast-enhanced dobutamine stress echocardiography. Circ J. 2007;71(7):1060-1066. PubMed, CrossRef
  12. Dehghan M, Mente A, Teo KK, Gao P, Sleight P, Dagenais G, Avezum A, Probstfield JL, Dans T, Yusu S. Relationship between healthy diet and risk of cardiovascular disease among patients on drug therapies for secondary prevention: a prospective cohort study of 31 546 high-risk individuals from 40 countries. Circulation. 2012;126(23):2705-2712. PubMed, CrossRef
  13. Imamura F, Micha R, Khatibzadeh S, Fahimi S, Shi P, Powles J, Mozaffarian D. Dietary quality among men and women in 187 countries in 1990 and 2010: a systematic assessment. Lancet Glob Health. 2015;3(3):e132-e142. PubMed, PubMedCentral, CrossRef
  14. Haque ATME, Yusoff FBM, Ariffin MHS, Hamid MF, Hashim SRB, Haque M. Lipid Profile of the Coronary Heart Disease (CHD) Patients Admitted in a Hospital in Malaysia. J App Pharm Sci. 2016;6(05):137-142. CrossRef
  15. Rambabu Kondredddy, Ali Chenak, Uma Shankar Akula, Addison Garabet, Shakila Srikumar, Abdalla M Jarari, Jagannadha Rao Peela. Study of Lipid Profile in Coronary Heart Disease patients in Libya. J Biomed Sci. 2012;1(4):3. CrossRef
  16. Kumar L, Das AL. Assessment of Serum Lipid Profile in Patients of Coronary Artery Disease: A Case-Control Study. Int J Contemp Med Res. 2018;5(5):E59-E62. CrossRef
  17. Zaribaf F, Mohammadifard N, Sarrafzadegan N, Karimi G, Gholampour A, Azadbakht L. Dietary patterns in relation to lipid profiles among Iranian adults. J Cardiovasc Thorac Res. 2019;11(1):19-27. PubMed, PubMedCentral, CrossRef
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